What is Rejuran?
Rejuran is an injectable skin treatment containing polynucleotides (PN) derived from salmon DNA. These molecules support the skin’s natural repair processes by improving hydration, elasticity, and overall skin quality. Rejuran is commonly used to address early signs of ageing, skin thinning, acne scarring, and compromised skin barrier function.
Unlike traditional volumising injectables, Rejuran focuses on skin regeneration and repair, rather than altering facial structure.
Rejuran is one of several injectable treatments used to improve skin quality. To understand how it compares with hydration-focused treatments, read our guide on Rejuran vs Skin Boosters.
What is Rejuran used for?
Rejuran may be used to support improvement in:
- Fine lines and crepey skin
- Dull or dehydrated skin
- Loss of elasticity and firmness
- Acne scarring and post-inflammatory skin changes
- Sun-damaged or environmentally stressed skin
Rejuran is often chosen by patients seeking gradual, natural-looking skin quality improvements rather than immediate visible volume.
How does Rejuran work?
Polynucleotides interact with skin cells to support:
- Cellular repair and renewal
- Improved skin hydration
- Enhanced collagen environment
- Strengthening of the skin barrier
Results develop progressively as the skin responds over time, rather than immediately after treatment.
Who is a suitable candidate for Rejuran?
Rejuran may be suitable for:
- Patients experiencing early signs of skin ageing
- Individuals with compromised or sensitised skin
- Patients seeking preventative skin treatments
- Those wanting to improve skin quality without volume changes
A consultation with a qualified health professional is required to determine suitability.
How many Rejuran treatments are needed?
A typical treatment plan may involve:
- 2–3 initial sessions, spaced approximately 3–4 weeks apart
- Maintenance treatments as advised, based on individual skin response
Your treatment plan will be personalised following consultation.
Is Rejuran safe in Australia?
Rejuran is widely used in medical aesthetic practice. As with all injectable treatments, it must be administered by appropriately qualified professionals following a consultation.
Possible side effects may include:
- Temporary redness
- Mild swelling
- Injection site tenderness
- Small bumps at injection points (usually resolving within days)
All risks, benefits, and aftercare instructions are discussed during consultation.
Is there downtime after Rejuran?
Most patients resume normal activities within 24–48 hours. Mild swelling or small raised areas at injection sites may occur and typically settle within several days.
Rejuran vs Skin Boosters: What’s the difference?
While both treatments focus on skin quality:
- Rejuran supports skin repair and regeneration
- Skin boosters primarily focus on hydration
In some treatment plans, both may be used together, depending on individual skin goals.
Rejuran at Illume Cosmetic Clinic
At Illume Cosmetic Clinic, Rejuran treatments are performed by AHPRA-registered nurses following a comprehensive consultation. Treatment plans are tailored to your skin concerns, goals, and medical history.
This information is general in nature and does not replace a personalised medical consultation. Individual results may vary.
FAQs
How long do Rejuran results last?
Results develop gradually over several weeks. Longevity varies depending on skin condition, lifestyle, and maintenance treatments.
Does Rejuran change face shape?
No. Rejuran is designed to improve skin quality, not add volume or alter facial structure.
Can Rejuran be combined with other treatments?
Yes. Rejuran may be combined with treatments such as microneedling, RF skin treatments, or skin boosters, depending on clinical assessment.
Is Rejuran suitable for sensitive skin?
Rejuran is often chosen for compromised or sensitive skin; however, suitability must be assessed during consultation.
Medical Oversight at Illume
All cosmetic medical treatments at this clinic are carried out under appropriate medical governance and in compliance with Australian regulatory requirements. All registered nurses work in collaboration with qualified medical practitioners or nurse practitioner who provide prescribing, oversight, and clinical support.
Every patient receives an individualised consultation and prescription from an authorised prescriber prior to treatment. Medications are administered in accordance with the relevant state and national regulations, ensuring the highest standard of patient safety and ethical care.


