What is Rejuran?

Rejuran is an injectable skin treatment containing polynucleotides (PN) derived from salmon DNA. Polynucleotides are used in aesthetic medicine to support skin repair processes, improve elasticity, and strengthen the skin barrier.


Rejuran is a polynucleotide-based injectable treatment used to support skin repair and improve skin quality. If you’re unfamiliar with this treatment, you can read our detailed guide explaining what Rejuran is and how it works.

Rejuran is not designed to add volume or change facial structure. Instead, it focuses on gradual improvements in skin quality, including texture, resilience, and overall skin health.

Rejuran may be considered for:

  • Skin thinning or fragility
  • Loss of elasticity
  • Acne scarring or post-inflammatory skin changes
  • Dull, compromised, or sensitised skin

What are skin boosters?

Skin boosters are injectable treatments primarily made from hyaluronic acid (HA). Unlike dermal fillers, skin boosters are designed to disperse evenly within the skin to improve hydration and surface smoothness rather than volume.

Skin boosters are commonly used to:

  • Improve skin hydration
  • Enhance glow and luminosity
  • Smooth fine lines related to dehydration
  • Support overall skin texture

They are often selected when dehydration is the primary contributor to skin concerns.


Rejuran vs Skin Boosters: Key differences

  • Feature

    Primary Purpose
    Key Ingredient
    Effect on Volume
    Results Timeline
    Best Suited for
  • Rejuran

    Skin Repair & Regeneration
    Polynucleotides (PN)

    None
    Gradual, progressive
    Skin quality decline, scarring, ageing
  • Skin Boosters

    Skin Hydration
    Hyaluronic acid (HA)
    None
    Faster hydration effect
    Dehydrated or dull skin


Which treatment is better?

There is no universally “better” option. The most appropriate treatment depends on why the skin is changing, not just how it looks.

  • Rejuran may be more suitable when skin repair, resilience, and texture are the main concerns.
  • Skin boosters may be more suitable when dehydration and loss of glow are the primary issues.

In many cases, a combination approach may be recommended following consultation.

Rejuran vs Skin Boosters by age

Skin needs evolve over time, which often influences treatment selection.

  • 20s: Skin boosters are commonly used to support hydration and early skin maintenance.
  • 30s: Some patients begin introducing Rejuran alongside skin boosters for preventative skin support.
  • 40s: Rejuran is often prioritised as skin repair and elasticity decline, with hydration treatments used as support.
  • 50s+: Rejuran may be used as a core skin quality treatment, depending on individual assessment.

Age alone does not determine suitability — skin condition and treatment goals are more important.

Can Rejuran and skin boosters be combined?

Yes. When clinically appropriate, Rejuran and skin boosters may be used together within a treatment plan to support both hydration and regenerative skin processes.

All combination treatments are planned following consultation with a qualified health professional.

Downtime and recovery

Both treatments are considered low-downtime.

You may experience:

  • Mild redness
  • Temporary swelling
  • Small raised injection points

Most patients resume normal activities within 24–48 hours. Individual recovery varies.

Rejuran vs Skin Boosters at Illume Cosmetic Clinic

At Illume Cosmetic Clinic, injectable skin treatments are performed by AHPRA-registered nurses following a comprehensive consultation. Treatment plans are tailored to individual skin concerns, medical history, and long-term skin goals.

This information is general in nature and does not replace personalised medical advice. Individual results vary.

Frequently Asked Questions

Does Rejuran last longer than skin boosters?

Rejuran supports longer-term improvements in skin quality, while skin boosters provide more immediate hydration effects. Longevity varies between individuals.

Do either treatments change face shape?

No. Neither Rejuran nor skin boosters are designed to add volume or alter facial structure.


Is one better for acne scarring?

Rejuran is often selected for scar-affected or compromised skin, though suitability must be assessed during consultation.

Medical Oversight at Illume

All cosmetic medical treatments at this clinic are carried out under appropriate medical governance and in compliance with Australian regulatory requirements. All registered nurses work in collaboration with qualified medical practitioners or nurse practitioner who provide prescribing, oversight, and clinical support.

Every patient receives an individualised consultation and prescription from an authorised prescriber prior to treatment. Medications are administered in accordance with the relevant state and national regulations, ensuring the highest standard of patient safety and ethical care.

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